Cep19 Gene Summary [Mouse]

Predicted to be involved in microtubule anchoring at centrosome and vesicle targeting, trans-Golgi to periciliary membrane compartment. Predicted to be located in cilium and nucleoplasm. Predicted to be active in microtubule cytoskeleton. Is expressed in axial skeleton; lower jaw; and lower jaw incisor. Orthologous to human CEP19 (centrosomal protein 19). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cep19
Official Name
centrosomal protein 19 [Source:MGI Symbol;Acc:MGI:1914244]
Ensembl ID
ENSMUSG00000035790
Bio databases IDs NCBI: 66994 Ensembl: ENSMUSG00000035790
Aliases centrosomal protein 19
Synonyms 1500031L02Rik, C3orf34, centrosomal protein 19, MOSPGF, RGD621352
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CEP19-like protein
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin resistance
  • obesity
  • weight gain
  • morbid obesity and spermatogenic failure
  • Bardet-Biedl syndrome
  • hyperphagia
regulated by
regulates
  • D-glucose
  • triacylglycerol
  • oxygen
  • RABL2A/B
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cilia
  • basal bodies
  • centrosome
  • centriole
  • cytosol
  • nucleoplasm
  • spindle pole

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep19 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cilium morphogenesis
  • microtubule anchoring at centrosome

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cilium basal body
  • centriole
  • cytoplasm
  • spindle pole
  • cilium
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.