Cep350 Gene Summary [Mouse]
Predicted to enable microtubule binding activity. Acts upstream of or within non-motile cilium assembly and protein localization to centrosome. Predicted to be located in centriole. Predicted to be active in centrosome. Is expressed in brain; lung; and testis. Orthologous to human CEP350 (centrosomal protein 350). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep350 |
| Official Name | centrosomal protein 350 [Source:MGI Symbol;Acc:MGI:1921331] |
| Ensembl ID | ENSMUSG00000033671 |
| Bio databases IDs | |
| Aliases | centrosomal protein 350 |
| Synonyms | 4933409L06Rik, 6430546F08Rik, CAP350, centrosomal protein 350, GM133 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep350 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RecF/RecN/SMC N terminal domain
- CAP-Gly domain
- protein binding
- CAP_GLY
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- cytoskeleton
- perinuclear region
- filamentous network
- Nucleus
- basal bodies
- centrosome
- centriole
- microtubules
- cytosol
- nuclear foci
- nucleoplasm
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep350 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- microtubule anchoring
- protein localization to centrosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- centriole
- membrane
- spindle
- cell projection
Molecular Function
What the gene product does at the molecular level
- protein binding
- microtubule binding