Iqce Gene Summary [Mouse]
Involved in positive regulation of transcription by RNA polymerase II; protein localization to motile cilium; and regulation of smoothened signaling pathway. Located in ciliary membrane and cytoplasmic side of plasma membrane. Part of plasma membrane protein complex. Orthologous to human IQCE (IQ motif containing E). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Iqce |
| Official Name | IQ motif containing E [Source:MGI Symbol;Acc:MGI:1921489] |
| Ensembl ID | ENSMUSG00000036555 |
| Bio databases IDs | |
| Aliases | IQ motif containing E |
| Synonyms | 1700028P05Rik, IQ motif containing E, KIAA1023, mKIAA1023, PAPA7, RGD1311349 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Iqce often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calmodulin-binding motif
- IQ (isoleucine-glutamine) motif containing G and D (IQCG and IQCD)
- protein binding
- IQ calmodulin-binding motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- cytoplasmic face of plasma membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Iqce gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- limb morphogenesis
Cellular Component
Where in the cell the gene product is active
- cilium
- cilium membrane
Molecular Function
What the gene product does at the molecular level
- protein binding