Ttc23 Gene Summary [Mouse]
Involved in positive regulation of smoothened signaling pathway. Located in cilium. Orthologous to human TTC23 (tetratricopeptide repeat domain 23). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Ttc23 |
| Official Name | tetratricopeptide repeat domain 23 [Source:MGI Symbol;Acc:MGI:1914259] |
| Ensembl ID | ENSMUSG00000030555 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat domain 23 |
| Synonyms | 1600012K10Rik, HCC-8, RGD1310409, tetratricopeptide repeat domain 23 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ttc23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of Unknown Function (DUF3856)
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cilia
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ttc23 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of smoothened signaling pathway
Cellular Component
Where in the cell the gene product is active
- cilium
Molecular Function
What the gene product does at the molecular level
- protein binding