Cpz Gene Summary [Mouse]
Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in peptide metabolic process and protein processing. Predicted to be located in extracellular matrix. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; ear; genitourinary system; integumental system; and nervous system. Orthologous to human CPZ (carboxypeptidase Z). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cpz |
| Official Name | carboxypeptidase Z [Source:MGI Symbol;Acc:MGI:88487] |
| Ensembl ID | ENSMUSG00000036596 |
| Bio databases IDs | |
| Aliases | carboxypeptidase Z |
| Synonyms | carboxypeptidase Z |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cpz often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc carboxypeptidase
- Zn_pept domain
- peptidase
- metallocarboxypeptidase
- Fz domain
- Peptidase_M14NE-CP-C_like
- M14 family of metallocarboxypeptidases and related proteins
- CarboxypepD_reg-like domain
- Carboxypeptidase regulatory-like domain
- CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain
Pathways
Biological processes and signaling networks where the Cpz gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cell surface
- intercellular junctions
- extracellular matrix
- cellular protrusions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cpz gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptide metabolic process
- proteolysis
- Wnt receptor signaling pathway
- protein processing
Cellular Component
Where in the cell the gene product is active
- extracellular space
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metallocarboxypeptidase activity