Etl4 Gene Summary [Mouse]

Involved in embryonic skeletal system development. Located in cytoplasm. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; sensory organ; and surface ectoderm. Orthologous to human KIAA1217 (KIAA1217). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Etl4
Official Name
enhancer trap locus 4 [Source:MGI Symbol;Acc:MGI:95454]
Ensembl ID
ENSMUSG00000036617
Bio databases IDs NCBI: 208618 Ensembl: ENSMUSG00000036617
Aliases enhancer trap locus 4
Synonyms 6620402G01RIK, 9430077C05RIK, E330027G05Rik, enhancer trap locus 4, ETL4, LOC681362, RGD1563437, SKT
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Etl4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • osteoarthritis
  • prostate cancer
  • dementia
  • spontaneous preterm birth
  • idiopathic scoliosis
  • COVID-19
  • frontal fibrosing alopecia
  • diverticular disease
  • sneeze
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • centrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Etl4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • embryonic skeletal system development

Cellular Component

Where in the cell the gene product is active
  • centrosome
  • cytoplasm

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.