Fam135b Gene Summary [Mouse]
Predicted to be involved in lipid metabolic process. Is expressed in medulla oblongata; spinal cord; and ventral grey horn. Orthologous to human FAM135B (family with sequence similarity 135 member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fam135b |
| Official Name | family with sequence similarity 135, member B [Source:MGI Symbol;Acc:MGI:1917613] |
| Ensembl ID | ENSMUSG00000036800 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 135, member B |
| Synonyms | 1700010C24RIK, A830008O07Rik, C8ORFK32, family with sequence similarity 135 member B, family with sequence similarity 135, member B, RGD1308133 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fam135b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein FAM135
- alpha/beta hydrolases
- Palmitoyl protein thioesterase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- periodontitis
- rectum cancer
- rectal adenocarcinoma
- colorectal carcinomagenesis
- Alzheimer disease
- dementia
- colon adenocarcinoma
- colon epithelial cancer
- gastroesophageal reflux
regulated by
- isoprenaline
- lithium chloride
- valproic acid
- CMTM3
regulates
role in cell
- proliferation
- oxaliplatin sensitivity
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fam135b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular lipid metabolic process