Syde2 Gene Summary [Mouse]
Predicted to enable GTPase activator activity. Predicted to be involved in cell migration and regulation of Ras protein signal transduction. Predicted to be active in synaptic membrane. Is expressed in spongiotrophoblast and trophectoderm. Orthologous to human SYDE2 (synapse defective Rho GTPase homolog 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Syde2 |
| Official Name | synapse defective 1, Rho GTPase, homolog 2 (C. elegans) [Source:MGI Symbol;Acc:MGI:3036264] |
| Ensembl ID | ENSMUSG00000036863 |
| Bio databases IDs | |
| Aliases | synapse defective 1, Rho GTPase, homolog 2 (C. elegans) |
| Synonyms | C430017H16Rik, RGD1564206, Syde2-ps1, synapse defective 1, Rho GTPase, homolog 2 (C. elegans), synapse defective Rho GTPase homolog 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Syde2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGAP domain
- GTPase activator
- GTPase-activator protein for Rho-like GTPases
- RhoGAP
- C2 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Syde2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of small GTPase mediated signal transduction
- signal transduction
- regulation of Ras protein signal transduction
- cell migration
Cellular Component
Where in the cell the gene product is active
- cytosol
- synaptic membrane
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity