SYDE2 Gene Summary [Human]
Predicted to enable GTPase activator activity. Acts upstream of or within cell migration. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SYDE2 |
| Official Name | synapse defective Rho GTPase homolog 2 [Source:HGNC Symbol;Acc:HGNC:25841] |
| Ensembl ID | ENSG00000097096 |
| Bio databases IDs | |
| Aliases | synapse defective Rho GTPase homolog 2 |
| Synonyms | C430017H16Rik, RGD1564206, Syde2-ps1, synapse defective 1, Rho GTPase, homolog 2 (C. elegans), synapse defective Rho GTPase homolog 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SYDE2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RhoGAP domain
- GTPase activator
- GTPase-activator protein for Rho-like GTPases
- RhoGAP
- C2 domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SYDE2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of small GTPase mediated signal transduction
- signal transduction
- regulation of Ras protein signal transduction
- cell migration
Cellular Component
Where in the cell the gene product is active
- cytosol
- synaptic membrane
Molecular Function
What the gene product does at the molecular level
- GTPase activator activity