Elac1 Gene Summary [Mouse]
Predicted to enable 3'-tRNA processing endoribonuclease activity. Predicted to be involved in rescue of stalled ribosome and tRNA 3'-end processing. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human ELAC1 (elaC ribonuclease Z 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elac1 |
| Official Name | elaC ribonuclease Z 1 [Source:MGI Symbol;Acc:MGI:1890495] |
| Ensembl ID | ENSMUSG00000036941 |
| Bio databases IDs | |
| Aliases | elaC ribonuclease Z 1 |
| Synonyms | 2610018O07RIK, 8430417G19Rik, D29, elaC ribonuclease Z 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Elac1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Beta-lactamase superfamily domain
- tRNA-specific ribonuclease
- enzyme
- metallo-hydrolase-like_MBL-fold
- ribonuclease Z
- tRNase Z endonuclease
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Elac1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rescue of stalled ribosome
- tRNA 3'-end processing
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- metal ion binding
- tRNA-specific ribonuclease activity
- 3'-tRNA processing endoribonuclease activity