Vim

Enables RNA binding activity. A structural constituent of cytoskeleton and structural constituent of eye lens. Involved in intermediate filament organization and positive regulation of gene expression. Acts upstream of or within several processes, including astrocyte differentiation; cellular response to type II interferon; and lens fiber cell development. Located in several cellular components, including cell leading edge; intermediate filament; and phagocytic vesicle. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Used to study cataract 30. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Vim often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Vim gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Vim gene, providing context for its role in the cell.