Mospd3 Gene Summary [Mouse]

Acts upstream of or within heart development. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in cerebral cortex subventricular zone; cerebral cortex ventricular layer; and cortical plate. Orthologous to human MOSPD3 (motile sperm domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mospd3
Official Name
motile sperm domain containing 3 [Source:MGI Symbol;Acc:MGI:1916179]
Ensembl ID
ENSMUSG00000037221
Bio databases IDs NCBI: 68929 Ensembl: ENSMUSG00000037221
Aliases motile sperm domain containing 3
Synonyms 1190005J19RIK, 5133401H10Rik, CDS3, Gtig2, motile sperm domain containing 3, NET30, R124
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mospd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • MSP (Major sperm protein) domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lipopolysaccharide
  • topotecan
  • diphtheria toxin
  • intestinal epithelial cells

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mospd3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • heart development

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding