MOSPD3 Gene Summary [Human]
This gene encodes a multi-pass membrane protein with a major sperm protein (MSP) domain. The deletion of a similar mouse gene is associated with defective cardiac development and neonatal lethality. Alternate transcriptional splice variants, encoding different isoforms, have been described. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | MOSPD3 |
| Official Name | motile sperm domain containing 3 [Source:HGNC Symbol;Acc:HGNC:25078] |
| Ensembl ID | ENSG00000106330 |
| Bio databases IDs | |
| Aliases | motile sperm domain containing 3 |
| Synonyms | 1190005J19RIK, 5133401H10Rik, CDS3, Gtig2, motile sperm domain containing 3, NET30, R124 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MOSPD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- MSP (Major sperm protein) domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MOSPD3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart development
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding