Zfp692 Gene Summary [Mouse]
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin insulator sequence binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and regulation of gluconeogenesis. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in chromosome. Is expressed in several structures, including 1st branchial arch; limb; male reproductive system; maxillary process; and urinary system. Orthologous to human ZNF692 (zinc finger protein 692). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp692 |
| Official Name | zinc finger protein 692 [Source:MGI Symbol;Acc:MGI:2144276] |
| Ensembl ID | ENSMUSG00000037243 |
| Bio databases IDs | |
| Aliases | zinc finger protein 692 |
| Synonyms | AREBP, FLJ20531, RGD1306740, Zfp692, Zfp692-ps, zinc finger protein 692 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp692 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- RNA polymerase II transcription regulatory region sequence-specific binding transcriptional repressor activity
- double-stranded DNA binding
- nucleic acid binding
- protein binding
- sequence-specific DNA binding
- C2H2-type zinc ribbon
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp692 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription from RNA polymerase II promoter
- regulation of gluconeogenesis
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- sequence-specific DNA binding transcription factor activity
- protein binding
- metal ion binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription