Imp4 Gene Summary [Mouse]
Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in fibrillar center. Predicted to be part of Mpp10 complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including axial musculature; extraembryonic component; submandibular gland primordium; thymus primordium; and vibrissa. Orthologous to human IMP4 (IMP U3 small nucleolar ribonucleoprotein 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Imp4 |
| Official Name | IMP4, U3 small nucleolar ribonucleoprotein [Source:MGI Symbol;Acc:MGI:106572] |
| Ensembl ID | ENSMUSG00000026127 |
| Bio databases IDs | |
| Aliases | IMP4, U3 small nucleolar ribonucleoprotein |
| Synonyms | BXDC4, D1WSU40E, IMP4, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 4, LRRGT00017, RGD1308463 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Imp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Imp4 domain
- coiled-coil domain
- Brix domain
- protein binding
- The Brix domain is found in a number of eukaryotic proteins
- Sigma-70 motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- fibrillar center
- pre-ribosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Imp4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
- ribosomal small subunit biogenesis
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- Mpp10 complex
- preribosome
- nucleolus
- fibrillar center
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- snoRNA binding
- protein binding
- rRNA primary transcript binding