Rps16 Gene Summary [Mouse]
A structural constituent of ribosome. Acts upstream of or within cellular response to leukemia inhibitory factor. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in early conceptus and secondary oocyte. Orthologous to human RPS16 (ribosomal protein S16). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rps16 |
| Official Name | ribosomal protein S16 [Source:MGI Symbol;Acc:MGI:98118] |
| Ensembl ID | ENSMUSG00000037563 |
| Bio databases IDs | |
| Aliases | ribosomal protein S16 |
| Synonyms | 40S ribosomal protein S16, ribosomal protein S16, S16, uS9 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps16 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- rpsI
- protein binding
- Ribosomal protein S9/S16
- RNA binding
Pathways
Biological processes and signaling networks where the Rps16 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- Alzheimer disease
- rheumatoid arthritis
- mucoepidermoid carcinoma
- myelodysplastic syndrome
regulates
- RNR
role in cell
- cell death
- replication in
- cell survival
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- interchromatin granule cluster fractions
- pre-ribosome
- cellular membrane
- ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps16 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- cytoplasmic translation
- ribosomal small subunit biogenesis
- rRNA processing
- translation
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- cytosolic ribosome
- cytosolic small ribosomal subunit
- synapse
- nucleolus
- nucleoplasm
- extracellular vesicular exosome
- focal adhesion
- cytoplasm
- membrane
- cytosol
- small ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome