Smim14 Gene Summary [Mouse]
Acts upstream of or within blastocyst hatching. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including bone; central nervous system; definitive endoderm; early conceptus; and secondary oocyte. Orthologous to human SMIM14 (small integral membrane protein 14). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Smim14 |
| Official Name | small integral membrane protein 14 [Source:MGI Symbol;Acc:MGI:1915802] |
| Ensembl ID | ENSMUSG00000037822 |
| Bio databases IDs | |
| Aliases | small integral membrane protein 14 |
| Synonyms | 1110003E01Rik, 1700127H04Rik, 5430439C17Rik, C4orf34, MAd4, RGD1311122, small integral membrane protein 14 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Smim14 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF2615)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Smim14 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- blastocyst hatching
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding