Atp5j2 Gene Summary [Mouse]
Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and skeleton. Orthologous to human ATP5MF (ATP synthase membrane subunit f). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp5j2 |
| Official Name | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 [Source:MGI Symbol;Acc:MGI:1927558] |
| Ensembl ID | ENSMUSG00000038690 |
| Bio databases IDs | |
| Aliases | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2 |
| Synonyms | 1110019H14Rik, ATP5J2, ATP5JL, ATPK, ATP synthase membrane subunit f, LOC684567 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp5j2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- adenosine-tetraphosphatase
- hydrogen-transporting ATP synthase activity, rotational mechanism
- transporter
Pathways
Biological processes and signaling networks where the Atp5j2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- Huntington disease
- chromophobe renal cell carcinoma
- chromophobe renal cancer
- infection by Influenza A virus subtype H1N1
regulates
- H+
role in cell
- autophagy
- autophagy in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- detergent resistant lipid raft fraction
- Mitochondria
- mitochondrial inner membrane
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp5j2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial ATP synthesis coupled proton transport
- ATP synthesis coupled proton transport
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- proton-transporting ATP synthase complex, coupling factor F(o)
- mitochondrion
- mitochondrial inner membrane
- mitochondrial proton-transporting ATP synthase complex
Molecular Function
What the gene product does at the molecular level
- hydrogen ion transporting ATP synthase activity, rotational mechanism