Josd2 Gene Summary [Mouse]
Enables deubiquitinase activity. Acts upstream of or within protein deubiquitination. Is active in cytoplasm. Is expressed in heart; node; and trigeminal ganglion. Orthologous to human JOSD2 (Josephin domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Josd2 |
| Official Name | Josephin domain containing 2 [Source:MGI Symbol;Acc:MGI:1913374] |
| Ensembl ID | ENSMUSG00000038695 |
| Bio databases IDs | |
| Aliases | Josephin domain containing 2 |
| Synonyms | 1110007C05Rik, Josephin domain containing 2, RGD1307305, SBBI54 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Josd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ubiquitin-specific protease
- enzyme
- protein binding
- Josephin
- ubiquitin-like-specific protease
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Josd2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein deubiquitination
- proteolysis
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- ubiquitin-specific protease activity
- protein binding