Sprr3 Gene Summary [Mouse]

Predicted to be involved in keratinization. Predicted to be located in Golgi apparatus and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and thymus. Orthologous to human SPRR3 (small proline rich protein 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sprr3
Official Name
small proline-rich protein 3 [Source:MGI Symbol;Acc:MGI:1330237]
Ensembl ID
ENSMUSG00000045539
Bio databases IDs NCBI: 20766 Ensembl: ENSMUSG00000045539
Aliases small proline-rich protein 3
Synonyms small proline-rich protein 3, SPR3
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sprr3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cornifin (SPRR) family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypoplasia
  • fibrosis
  • atherosclerosis
regulated by
regulates
role in cell
  • expression in
  • phosphorylation in
  • proliferation
  • activation in
  • interaction in
  • sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • perinuclear region
  • Golgi Apparatus

Gene-Specific Assays for Results You Can Trust

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