Cnst Gene Summary [Mouse]

Enables connexin binding activity. Predicted to be involved in positive regulation of Golgi to plasma membrane protein transport. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane; trans-Golgi network; and transport vesicle. Is expressed in cerebral cortex subventricular zone and cortical plate. Orthologous to human CNST (consortin, connexin sorting protein). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Cnst
Official Name
consortin, connexin sorting protein [Source:MGI Symbol;Acc:MGI:2445141]
Ensembl ID
ENSMUSG00000038949
Bio databases IDs NCBI: 226744 Ensembl: ENSMUSG00000038949
Aliases consortin, connexin sorting protein
Synonyms 9630058J23Rik, C1orf71, consortin, connexin sorting protein, LOC100134211, LOC100912475, PPP1R64, RGD1564833
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnst often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Consortin C-terminus
  • phosphatase binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • infection by HIV-1
  • osteoarthritis
regulated by
  • lipopolysaccharide
  • budesonide
  • ELL2

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • intracellular membrane-bounded organelle
  • Plasma Membrane
  • trans Golgi network
  • transport vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnst gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of Golgi to plasma membrane protein transport

Cellular Component

Where in the cell the gene product is active
  • trans-Golgi network
  • intracellular membrane-bounded organelle
  • membrane
  • macromolecular complex
  • transport vesicle
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phosphatase binding
  • protein binding
  • connexin binding

Gene-Specific Assays for Results You Can Trust

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