Tbc1d13 Gene Summary [Mouse]

Enables GTPase activator activity and small GTPase binding activity. Involved in intracellular protein transport. Located in cytosol and membrane. Orthologous to human TBC1D13 (TBC1 domain family member 13). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Tbc1d13
Official Name
TBC1 domain family, member 13 [Source:MGI Symbol;Acc:MGI:2385326]
Ensembl ID
ENSMUSG00000039678
Bio databases IDs NCBI: 70296 Ensembl: ENSMUSG00000039678
Aliases TBC1 domain family, member 13
Synonyms 2600014A06Rik, BC025586, TBC1 domain family member 13, TBC1 domain family, member 13
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tbc1d13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rab-GTPase-TBC domain
  • Domain in Tre-2, BUB2p, and Cdc16p
  • enzyme binding
  • GTPase activator
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • L-glutamic acid
  • phycocyanobilin
disease
  • eosinophilic esophagitis
role in cell
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tbc1d13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • intracellular protein transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • GTPase activator activity
  • small GTPase binding

Gene-Specific Assays for Results You Can Trust

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