Ndufa4l2 Gene Summary [Mouse]
Predicted to be part of respiratory chain complex IV. Is expressed in several structures, including brain; genitourinary system; heart; integumental system; and nose. Orthologous to human NDUFA4L2 (NDUFA4 mitochondrial complex associated like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ndufa4l2 |
| Official Name | Ndufa4, mitochondrial complex associated like 2 [Source:MGI Symbol;Acc:MGI:3039567] |
| Ensembl ID | ENSMUSG00000040280 |
| Bio databases IDs | |
| Aliases | Ndufa4, mitochondrial complex associated like 2 |
| Synonyms | COXFA4L2, LOC56901, MISTRH, NDUFA4 mitochondrial complex associated like 2, NDUFA4, mitochondrial complex associated like 2, NUOMS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ndufa4l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- NADH-ubiquinone reductase complex 1 MLRQ subunit
Pathways
Biological processes and signaling networks where the Ndufa4l2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- epithelial cancer
- epithelial neoplasia
- liver cancer
- lung adenocarcinoma formation
- endometrial adenocarcinoma
- endometrial adenocarcinoma formation
- renal clear cell adenocarcinoma
- renal clear cell cancer
- organismal death
role in cell
- proliferation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ndufa4l2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- mitochondrial respiratory chain complex IV