Wdr47 Gene Summary [Mouse]
Acts upstream of or within several processes, including detection of hot stimulus involved in thermoception; neuronal stem cell population maintenance; and telencephalon development. Located in several cellular components, including growth cone; microtubule; and neuronal cell body. Is expressed in several structures, including central nervous system; pancreas; respiratory system; sensory organ; and vibrissa. Orthologous to human WDR47 (WD repeat domain 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr47 |
| Official Name | WD repeat domain 47 [Source:MGI Symbol;Acc:MGI:2139593] |
| Ensembl ID | ENSMUSG00000040389 |
| Bio databases IDs | |
| Aliases | WD repeat domain 47 |
| Synonyms | 1810073M12Rik, mKIAA0893, RGD1309181, WD repeat domain 47 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- LisH-like dimerization domain
- binding protein
- WD40 repeats
- WD domain, G-beta repeat
- C-terminal to LisH motif
- WD40
- protein binding
- LisH
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubules
- growth cone
- neurites
- perikaryon
- axons
- dendrites
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cerebral cortex radial glia guided migration
- neural precursor cell proliferation
- autophagy
- negative regulation of microtubule depolymerization
- adult locomotory behavior
- microtubule cytoskeleton organization
- neuronal stem cell maintenance
- anterior commissure morphogenesis
- corpus callosum development
Cellular Component
Where in the cell the gene product is active
- growth cone
- dendrite
- cytoplasm
- neuronal cell body
- microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding