Atp13a1 Gene Summary [Mouse]
Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity; P-type ion transporter activity; and membrane protein dislocase activity. Predicted to be involved in extraction of mislocalized protein from ER membrane; intracellular calcium ion homeostasis; and transmembrane transport. Located in endoplasmic reticulum membrane. Orthologous to human ATP13A1 (ATPase 13A1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atp13a1 |
| Official Name | ATPase type 13A1 [Source:MGI Symbol;Acc:MGI:2180801] |
| Ensembl ID | ENSMUSG00000031862 |
| Bio databases IDs | |
| Aliases | ATPase type 13A1 |
| Synonyms | ATP13A, ATPase 13A1, ATPase type 13A1, catp, CGI-152 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Atp13a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- manganese-transporting ATPase
- heavy metal translocating P-type ATPase
- protein binding
- E1-E2 ATPase
- Cation transport ATPase (P-type)
- P-type ATPase of unknown pump specificity (type V)
- Haloacid Dehalogenase-like Hydrolases
- copper-(or silver)-translocating P-type ATPase
- ATPase, P-type (transporting), HAD superfamily, subfamily IC
- transporter
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- endoplasmic reticulum membrane
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Atp13a1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- manganese ion transmembrane transport
- ion transmembrane transport
- protein transport
- cellular calcium ion homeostasis
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- manganese-transporting ATPase activity
- ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
- cation-transporting ATPase activity
- metal ion binding