Elapor1 Gene Summary [Mouse]
Predicted to be involved in autophagosome assembly; cellular response to starvation; and positive regulation of autophagosome assembly. Predicted to be located in Golgi apparatus; bounding membrane of organelle; and endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Predicted to colocalize with late endosome; lysosome; and trans-Golgi network. Orthologous to human ELAPOR1 (endosome-lysosome associated apoptosis and autophagy regulator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Elapor1 |
| Official Name | endosome-lysosome associated apoptosis and autophagy regulator 1 [Source:MGI Symbol;Acc:MGI:1923930] |
| Ensembl ID | ENSMUSG00000040412 |
| Bio databases IDs | |
| Aliases | endosome-lysosome associated apoptosis and autophagy regulator 1 |
| Synonyms | 5330417C22Rik, EIG121, endosome-lysosome associated apoptosis and autophagy regulator 1, Iir, Inceptor, Insulin inhibitory receptor, KIAA1324, RGD1310209 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Elapor1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tyrosine-protein kinase ephrin type A/B receptor-like
- protein binding
- Tumor necrosis factor receptor superfamily (TNFRSF)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- lung adenocarcinoma formation
- primary genetic hyperlipidemia
- teratozoospermia
- endometriosis
- oligozoospermia
regulates
- insulin
- glycogen
- IGF1R/INSR
role in cell
- growth
- proliferation
- migration
- morphology
- contact growth inhibition
- organization
- assembly
- area
- response
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- lysosome
- trans Golgi network
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Elapor1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagic vacuole assembly
- positive regulation of autophagic vacuole assembly
- cellular response to starvation
- positive regulation of vacuole organization
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- late endosome membrane
- trans-Golgi network
- extracellular vesicular exosome
- late endosome
- lysosomal membrane
- plasma membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- RNA binding