Necab1 Gene Summary [Mouse]
Predicted to enable identical protein binding activity. Acts upstream of or within blastocyst hatching. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in early conceptus and telencephalon. Orthologous to human NECAB1 (N-terminal EF-hand calcium binding protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Necab1 |
| Official Name | N-terminal EF-hand calcium binding protein 1 [Source:MGI Symbol;Acc:MGI:1916602] |
| Ensembl ID | ENSMUSG00000040536 |
| Bio databases IDs | |
| Aliases | N-terminal EF-hand calcium binding protein 1 |
| Synonyms | 1700003H21Rik, EFCBP1, N-terminal EF-hand calcium binding protein 1, STIP-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Necab1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF hand
- EF-hand domain pair
- Antibiotic biosynthesis monooxygenase
- EFh
- protein binding
- identical protein binding
- NIPSNAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Necab1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- blastocyst hatching
- regulation of amyloid precursor protein biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- calcium ion binding