NECAB1 Gene Summary [Human]
Enables identical protein binding activity. Predicted to be involved in regulation of amyloid precursor protein biosynthetic process. Predicted to act upstream of or within blastocyst hatching. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | NECAB1 |
| Official Name | N-terminal EF-hand calcium binding protein 1 [Source:HGNC Symbol;Acc:HGNC:20983] |
| Ensembl ID | ENSG00000123119 |
| Bio databases IDs | |
| Aliases | N-terminal EF-hand calcium binding protein 1 |
| Synonyms | 1700003H21Rik, EFCBP1, N-terminal EF-hand calcium binding protein 1, STIP-1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NECAB1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- EF-hand, calcium binding motif
- EF hand
- EF-hand domain pair
- Antibiotic biosynthesis monooxygenase
- EFh
- protein binding
- identical protein binding
- NIPSNAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NECAB1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- blastocyst hatching
- regulation of amyloid precursor protein biosynthetic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- calcium ion binding