Cpne7 Gene Summary [Mouse]

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008]

Details

Type
Retained Intron
Official Symbol
Cpne7
Official Name
copine VII [Source:MGI Symbol;Acc:MGI:2142747]
Ensembl ID
ENSMUSG00000034796
Bio databases IDs NCBI: 102278 Ensembl: ENSMUSG00000034796
Aliases copine VII
Synonyms copine 7, copine VII
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cpne7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Copine
  • von Willebrand factor (vWF) type A domain
  • vWFA
  • protein binding
  • Protein kinase C conserved region 2 (CalB)
  • C2 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • schizophrenia
  • epithelial cancer
  • colorectal cancer
  • epithelial basal cell carcinoma
  • atopic dermatitis
regulated by
  • zinc pyrithione
  • ITK
  • molybdenum disulfide
  • IKZF1
  • 3,5-dihydroxyphenylglycine
  • pidnarulex
  • CHD4
regulates
  • lipid
  • ERK
role in cell
  • phosphorylation in
  • migration
  • proliferation
  • growth
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Nucleus
  • Plasma Membrane
  • synapse

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cpne7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular response to calcium ion
  • lipid metabolic process

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • extracellular vesicular exosome
  • cytoplasm
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • calcium-dependent phospholipid binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.