Rimklb Gene Summary [Mouse]
Enables N-acetyl-L-aspartate-L-glutamate ligase activity and citrate-L-glutamate ligase activity. Predicted to be involved in protein modification process. Located in cytoplasm. Is expressed in several structures, including central nervous system; eye; genitourinary system; hindlimb phalanx; and tooth. Orthologous to human RIMKLB (ribosomal modification protein rimK like family member B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rimklb |
| Official Name | ribosomal modification protein rimK-like family member B [Source:MGI Symbol;Acc:MGI:1918325] |
| Ensembl ID | ENSMUSG00000040649 |
| Bio databases IDs | |
| Aliases | ribosomal modification protein rimK-like family member B |
| Synonyms | 4931417E21Rik, 4933426K21Rik, AI325948, AU015629, FAM80B, LOC100506112, LOC100912518, LOC103692220, NAAGS, NAAGS-I, RGD1560851, ribosomal modification protein rimK-like family member B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rimklb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Carbamoyl-phosphate synthase L chain, ATP binding domain
- ATP-grasp domain
- enzyme
- alpha-L-glutamate ligase, RimK family
- RimK-like ATP-grasp domain
- carbon-nitrogen bond forming ligase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rimklb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glutamine family amino acid metabolic process
- protein modification process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- citrate-L-glutamate ligase activity
- metal ion binding
- N-acetyl-L-aspartate-L-glutamate ligase activity