Cep128 Gene Summary [Mouse]

Acts upstream of or within regulation of gene expression and sperm flagellum assembly. Located in centriole. Orthologous to human CEP128 (centrosomal protein 128). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Cep128
Official Name
centrosomal protein 128 [Source:MGI Symbol;Acc:MGI:1922466]
Ensembl ID
ENSMUSG00000061533
Bio databases IDs NCBI: 75216 Ensembl: ENSMUSG00000061533
Aliases centrosomal protein 128
Synonyms 4930534B04Rik, 5430424K18Rik, AI449708, AI480494, C14orf145, C14orf61, centrosomal protein 128, E230024F20, LEDP/132
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cep128 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Mitotic checkpoint protein
  • chromosome segregation protein SMC, common bacterial type
  • RecF/RecN/SMC N terminal domain
  • RIM-binding protein of the cytomatrix active zone
  • chromosome segregation protein SMC, primarily archaeal type
  • exonuclease SbcC
  • Synaptonemal complex protein 1 (SCP-1)
  • Growth-arrest specific micro-tubule binding
  • helix-rich Mycoplasma protein
  • Calcium binding and coiled-coil domain (CALCOCO1) like

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • organismal death
  • idiopathic pulmonary fibrosis
  • ulcerative colitis
  • hypothyroidism
regulated by
role in cell
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • basal bodies
  • centrosome
  • Golgi Apparatus
  • centriole
  • spindle pole
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cep128 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein localization
  • regulation of gene expression

Cellular Component

Where in the cell the gene product is active
  • nuclear membrane
  • centrosome
  • centriole
  • spindle pole
  • Golgi apparatus

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.