Osbpl10 Gene Summary [Mouse]
Predicted to enable cholesterol binding activity and phosphatidylserine binding activity. Predicted to be involved in lipid metabolic process and lipid transport. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in cytosol and membrane. Is expressed in several structures, including genitourinary system; heart; immune system; lung; and nervous system. Orthologous to human OSBPL10 (oxysterol binding protein like 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Osbpl10 |
| Official Name | oxysterol binding protein-like 10 [Source:MGI Symbol;Acc:MGI:1921736] |
| Ensembl ID | ENSMUSG00000040875 |
| Bio databases IDs | |
| Aliases | oxysterol binding protein-like 10 |
| Synonyms | 4933433D06Rik, C820004B04RIK, OPR-10, ORP-10, OSBP9, oxysterol binding protein-like 10, RGD1561652 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Osbpl10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phospholipid binding
- cholesterol binding
- binding protein
- phospholipid transporter
- PH domain
- protein binding
- Pleckstrin homology-like domain
- Oxysterol-binding protein
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- periodontitis
- COVID-19
- Parkinson disease
- Down syndrome
- peripheral arterial disease
- digestive system disorder
- Hutchinson-Gilford progeria syndrome
- glomerulonephritis
- cervical cancer
regulates
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Osbpl10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phospholipid transport
- phosphatidylserine acyl-chain remodeling
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- phosphatidylserine binding
- phospholipid transporter activity
- protein binding
- cholesterol binding