Prima1 Gene Summary [Mouse]
Enables enzyme binding activity and protein-membrane adaptor activity. Acts upstream of or within establishment of localization in cell. Located in plasma membrane. Orthologous to human PRIMA1 (proline rich membrane anchor 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Prima1 |
| Official Name | proline rich membrane anchor 1 [Source:MGI Symbol;Acc:MGI:1926097] |
| Ensembl ID | ENSMUSG00000041669 |
| Bio databases IDs | |
| Aliases | proline rich membrane anchor 1 |
| Synonyms | B230212M13RIK, BB120497, LOC683544, PRIMA, Prima1l, proline rich membrane anchor 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prima1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Proline-rich membrane anchor 1
- protein binding activity, bridging
- enzyme binding
- protein binding
- proline-rich attachment domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- major depression
- COVID-19
- streptozotocin-induced diabetic nephropathy
- colorectal cancer
- nocturnal frontal lobe epilepsy
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- membrane rafts
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Prima1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- anchoring junction
- synapse
- plasma membrane