Gpr155 Gene Summary [Mouse]
Predicted to enable cholesterol binding activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; cellular response to cholesterol; and regulation of signal transduction. Predicted to be active in lysosomal membrane. Is expressed in several structures, including brain; genitourinary system; liver; spinal cord; and spleen. Orthologous to human GPR155 (G protein-coupled receptor 155). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gpr155 |
| Official Name | G protein-coupled receptor 155 [Source:MGI Symbol;Acc:MGI:1915776] |
| Ensembl ID | ENSMUSG00000041762 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 155 |
| Synonyms | 1110017O10RIK, DEP.7, DEPDC3, F730029F15Rik, G protein-coupled receptor 155, LYCHOS, PGR22 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr155 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
- DEP
- cholesterol binding
- Membrane transport protein
Pathways
Biological processes and signaling networks where the Gpr155 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- lysosome membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr155 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of BMP signaling pathway
- transmembrane transport
- cognition
- cellular response to amino acid starvation
- cellular response to cholesterol
- intracellular signal transduction
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- cholesterol binding