Ammecr1 Gene Summary [Mouse]
Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in midface hypoplasia, hearing impairment, elliptocytosis, and nephrocalcinosis. Orthologous to human AMMECR1 (AMMECR nuclear protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ammecr1 |
| Official Name | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 [Source:MGI Symbol;Acc:MGI:1860206] |
| Ensembl ID | ENSMUSG00000042225 |
| Bio databases IDs | |
| Aliases | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
| Synonyms | 6230420G18Rik, AMMECR nuclear protein 1, AMMERC1, LOC286505, MFHIEN, RGD1561004 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ammecr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- AMMECR1
- PRK00801
- AmmeMemoRadiSam system protein A
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Mitochondria
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ammecr1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- mitochondrion
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding