Fbrs Gene Summary [Mouse]

Enables growth factor activity. Acts upstream of or within positive regulation of fibroblast proliferation. Located in extracellular space. Orthologous to human FBRS (fibrosin). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fbrs
Official Name
fibrosin [Source:MGI Symbol;Acc:MGI:104648]
Ensembl ID
ENSMUSG00000042423
Bio databases IDs NCBI: 14123 Ensembl: ENSMUSG00000042423
Aliases fibrosin
Synonyms FBS, FBS1, Fibrosin
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fbrs often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Autism susceptibility gene 2 protein
  • cytokine
  • growth factor

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • light chain associated amyloidosis
regulated by
  • 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene
  • CTNNB1
  • NR1I3
  • Yersinia pestis
  • SH-SY5Y cells
  • MYC
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Nucleus

Gene-Specific Assays for Results You Can Trust

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