Ube2q1 Gene Summary [Mouse]

Enables ubiquitin conjugating enzyme activity. Acts upstream of or within several processes, including embryo implantation; prolactin secretion; and suckling behavior. Predicted to be located in cytosol and filopodium. Predicted to be active in nucleus. Is expressed in several structures, including 4-cell stage embryo; blastocyst; mammary gland; reproductive system; and spleen. Orthologous to human UBE2Q1 (ubiquitin conjugating enzyme E2 Q1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ube2q1
Official Name
ubiquitin-conjugating enzyme E2Q family member 1 [Source:MGI Symbol;Acc:MGI:1917343]
Ensembl ID
ENSMUSG00000042572
Bio databases IDs NCBI: 70093 Ensembl: ENSMUSG00000042572
Aliases ubiquitin-conjugating enzyme E2Q family member 1
Synonyms 1110002C01Rik, 2310012M18Rik, GTAP, NICE-5, PRO3094, UBE2Q, ubiquitin conjugating enzyme E2 Q1, ubiquitin-conjugating enzyme E2Q family member 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ube2q1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ubiquitin conjugating enzyme
  • UBCc_UEV
  • enzyme
  • protein binding

Pathways

Biological processes and signaling networks where the Ube2q1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • chronic obstructive pulmonary disease
regulated by
regulates
role in cell
  • cell death
  • fertilization

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ube2q1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mating behavior
  • protein polyubiquitination
  • suckling behavior
  • fertilization
  • embryo implantation
  • prolactin secretion

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytosol
  • filopodium

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.