Bmt2 Gene Summary [Mouse]
Predicted to enable S-adenosyl-L-methionine binding activity. Predicted to be involved in cellular response to amino acid starvation; cellular response to methionine; and regulation of TORC1 signaling. Orthologous to human SAMTOR (S-adenosylmethionine sensor upstream of mTORC1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bmt2 |
| Official Name | base methyltransferase of 25S rRNA 2 [Source:MGI Symbol;Acc:MGI:2141466] |
| Ensembl ID | ENSMUSG00000042742 |
| Bio databases IDs | |
| Aliases | base methyltransferase of 25S rRNA 2 |
| Synonyms | B630005N14Rik, BMT2, C7orf60, FLJ31818, S-adenosylmethionine sensor upstream of mTORC1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bmt2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bmt2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to methionine
- cellular response to amino acid starvation
- methylation
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- methyltransferase activity