Acad11 Gene Summary [Mouse]
Predicted to enable long-chain fatty acyl-CoA dehydrogenase activity; medium-chain fatty acyl-CoA dehydrogenase activity; and very-long-chain fatty acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrion. Is expressed in central nervous system and retina. Orthologous to human ACAD11 (acyl-CoA dehydrogenase family member 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Acad11 |
| Official Name | acyl-Coenzyme A dehydrogenase family, member 11 [Source:MGI Symbol;Acc:MGI:2143169] |
| Ensembl ID | ENSMUSG00000090150 |
| Bio databases IDs | |
| Aliases | acyl-Coenzyme A dehydrogenase family, member 11 |
| Synonyms | 5730439E10Rik, acyl-CoA dehydrogenase family member 11, acyl-CoA dehydrogenase family, member 11, acyl-Coenzyme A dehydrogenase family, member 11, RGD1306270 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Acad11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- acyl-CoA dehydrogenase
- Protein Kinases, catalytic domain
- Acyl-CoA dehydrogenase, C-terminal domain
- Acyl-CoA dehydrogenase, middle domain
- Phosphotransferase enzyme family
- enzyme
- protein binding
- very-long-chain acyl-CoA dehydrogenase
- long-chain-acyl-CoA dehydrogenase
- Acyl-CoA dehydrogenase, N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- mitochondrial membrane
- mitochondrial inner membrane
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Acad11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- fatty acid beta-oxidation using acyl-CoA dehydrogenase
- fatty acid beta-oxidation
Cellular Component
Where in the cell the gene product is active
- peroxisome
- nucleus
- mitochondrial membrane
- cytoplasm
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- acyl-CoA dehydrogenase activity
- protein binding
- medium-chain-acyl-CoA dehydrogenase activity
- flavin adenine dinucleotide binding
- very-long-chain-acyl-CoA dehydrogenase activity
- long-chain-acyl-CoA dehydrogenase activity