Mif4gd Gene Summary [Mouse]
Predicted to enable identical protein binding activity and translation activator activity. Predicted to be involved in cap-dependent translational initiation and regulation of translational initiation. Predicted to be located in Golgi apparatus and nucleolus. Predicted to be part of histone mRNA stem-loop binding activity complex. Predicted to be active in cytosol. Is expressed in several structures, including aorta; brain; connective tissue; endocrine gland; and genitourinary system. Orthologous to human MIF4GD (MIF4G domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mif4gd |
| Official Name | MIF4G domain containing [Source:MGI Symbol;Acc:MGI:1916924] |
| Ensembl ID | ENSMUSG00000020743 |
| Bio databases IDs | |
| Aliases | MIF4G domain containing |
| Synonyms | 1110014L05Rik, 2310075G12Rik, AD023, MIF4G domain containing, MIFD, RGD1309685, SLIP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mif4gd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MIF4G domain
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- epithelial cancer
- neoplasia
- hepatocellular carcinoma
- liver cancer
- organismal death
regulates
- histone
- CDKN1B
role in cell
- cell death
- proliferation
- stabilization in
- phosphorylation in
- colony formation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Golgi Apparatus
- cytosol
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mif4gd gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of translation
- cap-dependent translational initiation
- regulation of translational initiation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
- Golgi apparatus
- nucleolus
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- RNA binding
- translation activator activity