Krtcap2 Gene Summary [Mouse]

Predicted to enable enzyme activator activity. Predicted to be involved in protein N-linked glycosylation. Part of oligosaccharyltransferase complex. Is expressed in several structures, including central nervous system and eye. Orthologous to human KRTCAP2 (keratinocyte associated protein 2). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Retained Intron
Official Symbol
Krtcap2
Official Name
keratinocyte associated protein 2 [Source:MGI Symbol;Acc:MGI:1913309]
Ensembl ID
ENSMUSG00000042747
Bio databases IDs NCBI: 66059 Ensembl: ENSMUSG00000042747
Aliases keratinocyte associated protein 2
Synonyms 0610010I12Rik, KCP2, keratinocyte associated protein 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krtcap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Keratinocyte-associated protein 2
  • protein binding activity, bridging
  • enzyme
  • enzyme activator activity

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • Behcet disease
  • allergy
  • gastric carcinoma
  • gastric epithelial cancer
  • ectopic pregnancy
  • systemic autoimmune syndrome
regulates
  • asparagine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Krtcap2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein N-linked glycosylation
  • protein N-linked glycosylation via arginine

Cellular Component

Where in the cell the gene product is active
  • oligosaccharyltransferase complex

Molecular Function

What the gene product does at the molecular level
  • enzyme activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.