Acot6 Gene Summary [Mouse]
Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Predicted to be located in cytosol. Is expressed in respiratory system cartilage; sensory organ; skeleton; and tarsus. Orthologous to human ACOT6 (acyl-CoA thioesterase 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Acot6 |
| Official Name | acyl-CoA thioesterase 6 [Source:MGI Symbol;Acc:MGI:1921287] |
| Ensembl ID | ENSMUSG00000043487 |
| Bio databases IDs | |
| Aliases | acyl-CoA thioesterase 6 |
| Synonyms | 4632408A20Rik, A330054B07, acyl-CoA thioesterase 6, c14 5530, C14orf42, LOC679313, RGD1309669 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Acot6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Serine hydrolase (FSH1)
- Prolyl oligopeptidase family
- alpha/beta hydrolases
- Acyl-CoA thioester hydrolase/BAAT N-terminal region
- enzyme
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- peroxisomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Acot6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acyl-CoA metabolic process
- fatty acid metabolic process
Cellular Component
Where in the cell the gene product is active
- cytosol
- peroxisomal matrix
Molecular Function
What the gene product does at the molecular level
- acyl-CoA hydrolase activity
- carboxylic ester hydrolase activity