Acot6 Gene Summary [Rat]

Predicted to enable acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Acot6
Official Name
acyl-CoA thioesterase 6 [Source:RGD Symbol;Acc:1309669]
Ensembl ID
ENSRNOG00000029637
Bio databases IDs NCBI: 299193 Ensembl: ENSRNOG00000029637
Aliases acyl-CoA thioesterase 6
Synonyms 4632408A20Rik, A330054B07, acyl-CoA thioesterase 6, c14 5530, C14orf42, LOC679313, RGD1309669
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Acot6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Serine hydrolase (FSH1)
  • Prolyl oligopeptidase family
  • alpha/beta hydrolases
  • Acyl-CoA thioester hydrolase/BAAT N-terminal region
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
regulated by
regulates
  • phytanic acid
  • pristanic acid

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol
  • peroxisomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Acot6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • acyl-CoA metabolic process
  • fatty acid metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytosol
  • peroxisomal matrix

Molecular Function

What the gene product does at the molecular level
  • acyl-CoA hydrolase activity
  • carboxylic ester hydrolase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.