Cilp2 Gene Summary [Mouse]
Predicted to enable carbohydrate binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including heart; liver; lung; musculoskeletal system; and spleen. Orthologous to human CILP2 (cartilage intermediate layer protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cilp2 |
| Official Name | cartilage intermediate layer protein 2 [Source:MGI Symbol;Acc:MGI:1915959] |
| Ensembl ID | ENSMUSG00000044006 |
| Bio databases IDs | |
| Aliases | cartilage intermediate layer protein 2 |
| Synonyms | 1110031K21Rik, cartilage intermediate layer protein 2, CLIP-2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cilp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Thrombospondin type 1 repeats
- Thrombospondin type 1 domain
- Mucin-2 protein WxxW repeating region
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- Peptidase_M14NE-CP-C_like
- Spondin-like TSP1 domain
- Carboxypeptidase regulatory-like domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- interterritorial matrix
- extrafibrillar region
- cell-associated matrix
- cell periphery
- extracellular matrix
- collagen fibrils
- cartilage matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cilp2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- nucleotide diphosphatase activity
- alkaline phosphatase activity