Pfn3 Gene Summary [Mouse]

Predicted to enable actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly and regulation of actin filament polymerization. Predicted to be located in cytoskeleton and nucleus. Predicted to be active in cytoplasm. Orthologous to human PFN3 (profilin 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pfn3
Official Name
profilin 3 [Source:MGI Symbol;Acc:MGI:2178800]
Ensembl ID
ENSMUSG00000044444
Bio databases IDs NCBI: 75477 Ensembl: ENSMUSG00000044444
Aliases profilin 3
Synonyms 1700012P12Rik, LOC684227, profilin-3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pfn3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PROF
  • actin binding
  • Profilin
  • protein binding

Pathways

Biological processes and signaling networks where the Pfn3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pfn3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of actin filament polymerization
  • positive regulation of actin filament bundle assembly
  • actin cytoskeleton organization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoskeleton
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • actin binding
  • lipid binding

Gene-Specific Assays for Results You Can Trust

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