Kcng4 Gene Summary [Mouse]

Predicted to enable delayed rectifier potassium channel activity; potassium channel regulator activity; and transmembrane transporter binding activity. Predicted to be involved in action potential; potassium ion transmembrane transport; and regulation of potassium ion transmembrane transport. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Is expressed in central nervous system; gut; male reproductive gland or organ; and retina inner nuclear layer. Orthologous to human KCNG4 (potassium voltage-gated channel modifier subfamily G member 4). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Kcng4
Official Name
potassium voltage-gated channel, subfamily G, member 4 [Source:MGI Symbol;Acc:MGI:1913983]
Ensembl ID
ENSMUSG00000045246
Bio databases IDs NCBI: 66733 Ensembl: ENSMUSG00000045246
Aliases potassium voltage-gated channel, subfamily G, member 4
Synonyms 4921535I01Rik, KV6.3, KV6.4, potassium voltage-gated channel modifier subfamily G member 4, potassium voltage-gated channel, subfamily G, member 4
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kcng4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NAB domain
  • delayed rectifier potassium channel
  • Ion transport protein
  • Broad-Complex, Tramtrack and Bric a brac
  • BTB_POZ
  • potassium channel regulator
  • ion channel binding
  • ion channel

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • familial multiple sclerosis
regulated by
regulates
  • K+

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • Endoplasmic Reticulum
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Kcng4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport
  • protein homooligomerization
  • regulation of action potential

Cellular Component

Where in the cell the gene product is active
  • voltage-gated potassium channel complex
  • membrane
  • plasma membrane
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • delayed rectifier potassium channel activity
  • ion channel binding

Gene-Specific Assays for Results You Can Trust

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