Mfsd5 Gene Summary [Mouse]

Predicted to enable molybdate ion transmembrane transporter activity. Acts upstream of or within response to food and response to starvation. Predicted to be located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and spinal cord. Orthologous to human MFSD5 (major facilitator superfamily domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mfsd5
Official Name
major facilitator superfamily domain containing 5 [Source:MGI Symbol;Acc:MGI:2145901]
Ensembl ID
ENSMUSG00000045665
Bio databases IDs NCBI: 106073 Ensembl: ENSMUSG00000045665
Aliases major facilitator superfamily domain containing 5
Synonyms AW556797, D15Mgi27, hsMOT2, major facilitator superfamily domain containing 5, MGC11308, RGD1305138, SLC61A1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfsd5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Major Facilitator Superfamily
  • protein binding
  • transporter
  • molybdate ion transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
regulated by
  • ASPSCR1-TFE3
  • RHO
  • camptothecin
regulates
  • molybdate

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfsd5 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ion transport
  • molybdate ion transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • molybdate ion transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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