Smtnl2 Gene Summary [Mouse]

Is expressed in several structures, including adipose tissue; femur; heart; lung; and metanephros. Orthologous to human SMTNL2 (smoothelin like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Smtnl2
Official Name
smoothelin-like 2 [Source:MGI Symbol;Acc:MGI:2442764]
Ensembl ID
ENSMUSG00000045667
Bio databases IDs NCBI: 276829 Ensembl: ENSMUSG00000045667
Aliases smoothelin-like 2
Synonyms D130058I21Rik, LOC687788, smoothelin-like 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Smtnl2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calponin homology domain
  • calponin homology (CH) domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • rotator cuff injury
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Smtnl2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • actin cytoskeleton organization

Cellular Component

Where in the cell the gene product is active
  • microtubule organizing center
  • filamentous actin

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.