Tent5b Gene Summary [Mouse]
Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of cell population proliferation; and positive regulation of gene expression. Predicted to be located in cytoplasm and nucleus. Orthologous to human TENT5B (terminal nucleotidyltransferase 5B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tent5b |
| Official Name | terminal nucleotidyltransferase 5B [Source:MGI Symbol;Acc:MGI:2140500] |
| Ensembl ID | ENSMUSG00000046694 |
| Bio databases IDs | |
| Aliases | terminal nucleotidyltransferase 5B |
| Synonyms | 4732473B16Rik, FAM46, FAM46B, MGC16491, RGD1308967, terminal nucleotidyltransferase 5B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tent5b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- nucleotidyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tent5b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of translation
- negative regulation of cell proliferation
- negative regulation of apoptotic process
- mRNA stabilization
- negative regulation of cell cycle
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding