Adck2 Gene Summary [Mouse]
Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Involved in regulation of ubiquinone biosynthetic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Used to study mitochondrial myopathy. Orthologous to human ADCK2 (aarF domain containing kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adck2 |
| Official Name | aarF domain containing kinase 2 [Source:MGI Symbol;Acc:MGI:1889336] |
| Ensembl ID | ENSMUSG00000046947 |
| Bio databases IDs | |
| Aliases | aarF domain containing kinase 2 |
| Synonyms | AA408112, AARF, aarF domain containing kinase 2, BB006057 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adck2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- protein kinase
- Protein Kinases, catalytic domain
- protein binding
- 2-polyprenylphenol 6-hydroxylase
- ABC1 atypical kinase-like domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adck2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of ubiquinone biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- protein serine/threonine kinase activity